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                                                            INNOVATIVE SOLUTIONS ADVANCING TREATMENT FOR GENETIC DISEASES

Osteoporosis

The Surgeon General’s Report on Bone Health and Osteoporosis estimates that in 2020 approximately half of Americans over age 50 will have or be a risk of developing osteoporosis.  The National Osteoporosis Foundation estimates roughly 10 million active cases in the U.S., 8 million women and 2 million men, with an additional 34 million Americans at serious risk of osteoporosis. Osteoporosis is responsible for more than 1.5 million fractures annually, including over 300,000 hip fractures; approximately 700,000 vertebral fractures; 250,000 wrist fractures; and 300,000 fractures at other sites. The estimated national direct expenditures (hospitals and nursing homes) for osteoporotic hip fractures were $18 billion dollars in 2002. Patients with hip fractures are much more likely to experience additional fractures in the future. The loss of quality of life underlying these statistics is enormous.